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Human HepG2 Proteomics DIA-MS limma Drug Perturbation

HepG2 Drug-Perturbation Proteomics: Mechanism-of-Action Analysis of 172 Compounds

DIA-MS proteomic profiling of 172 drugs in HepG2 cells. limma differential abundance across 8,630 proteins, per-drug response signatures, drug clustering, and Hallmark pathway enrichment to generate mechanism-of-action hypotheses.

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